Zephex® 134a

Leading medical propellant used in MDIs throughout the world

Our state-of-the-art manufacturing facilities in the North West of England have been designed and constructed to stringent current Good Manufacturing Practice (cGMP) standards.

The Zephex® facility in Cheshire, UK is the only one of its kind to have received an FDA audit, as well as inspections by the UK Medicines and Healthcare Products Regulatory Agency (MHRA), ensuring we remain at the leading edge of industry cGMP compliance.

Zephex® 134a analytical techniques have been confirmed to be equivalent if not better than those described in the Norflurane European Pharmacopeia (EP) Monograph. Zephex® 134a meets the requirement of our more stringent Mexichem specification and the requirements of IPACT1.

Physical properties of Zephex® 134a

PROPERTY	CONDITION	UNITS	VALUE
Molecular Weight			102.03
Boiling Point	1 atm	°C	-26.1
Melting Point		°C	-103.0
Critical Temperature		°C	101.0
Critical Pressure		bara	40.56
Critical Volume		m³/kg	1.97 × 10⁻³
Critical Density		kg/m³	507.6
Saturated Vapour Density at nBPt		kg/m³	5.26
Vapour Pressure	25°C	bara	6.652
Latent Heat of Evaporation at nBPt			216.8
Coefficient of Thermal Expansion	LIQ. 0–20°C	°C	0.002766
Solubility of HFA 134a in Water	20°C / 1 atm	% w/w	0.0773
Solubility of Water in HFA 134a	25°C / 1 atm	% w/w	0.11
Flammability in Air	1 atm		None
Autoignition Temperature		°C	770
Liquid Dielectric Constant	25°C		9.51
Vapour Dielectric Constant	25°C / 1 atm		1.014
Dielectric Strength	R12 = 1		0.5
Dipole Moment			2.06

Continued supply of Zephex® 134a in line with market needs

Supporting patients and partners worldwide with the continued supply of 134a.

More details

Document downloads

Zephex 134a Continued Supply Slide Deck (EN-UK)

Preview Download

Zephex 134a Flyer (EN-UK)

Preview Download

See More Speak with one of our experts

Speak with one of our experts

Do you have a question regarding medical propellants for one of our experts?

See More Product finder

Product finder

Browse OF&EM’s product portfolio

view all related articles

Announcement

Pharma

Zephex

Media Center

The transition in action: When innovation meets collaboration, even the sky isn’t the limit

21 January 2026

Press Release

OF&EM

Pharma

Media Center

Orbia Fluor & Energy Materials delivers first ISO tank of low-GWP propellant

14 October 2025

Press Release

Announcement

OF&EM

Media Center

Orbia Fluor & Energy Materials unveils new team to lead pharmaceutical division

19 March 2025

Loading page...

Leading medical propellant used in MDIs throughout the world

Our state-of-the-art manufacturing facilities in the North West of England have been designed and constructed to stringent current Good Manufacturing Practice (cGMP) standards.

Physical properties of Zephex® 134a

PROPERTY	CONDITION	UNITS	VALUE
Molecular Weight			102.03
Boiling Point	1 atm	°C	-26.1
Melting Point		°C	-103.0
Critical Temperature		°C	101.0
Critical Pressure		bara	40.56
Critical Volume		m³/kg	1.97 × 10⁻³
Critical Density		kg/m³	507.6
Saturated Vapour Density at nBPt		kg/m³	5.26
Vapour Pressure	25°C	bara	6.652
Latent Heat of Evaporation at nBPt			216.8
Coefficient of Thermal Expansion	LIQ. 0–20°C	°C	0.002766
Solubility of HFA 134a in Water	20°C / 1 atm	% w/w	0.0773
Solubility of Water in HFA 134a	25°C / 1 atm	% w/w	0.11
Flammability in Air	1 atm		None
Autoignition Temperature		°C	770
Liquid Dielectric Constant	25°C		9.51
Vapour Dielectric Constant	25°C / 1 atm		1.014
Dielectric Strength	R12 = 1		0.5
Dipole Moment			2.06

Leading medical propellant used in MDIs throughout the world

Our state-of-the-art manufacturing facilities in the North West of England have been designed and constructed to stringent current Good Manufacturing Practice (cGMP) standards.

Physical properties of Zephex® 134a

PROPERTY	CONDITION	UNITS	VALUE
Molecular Weight			102.03
Boiling Point	1 atm	°C	-26.1
Melting Point		°C	-103.0
Critical Temperature		°C	101.0
Critical Pressure		bara	40.56
Critical Volume		m³/kg	1.97 × 10⁻³
Critical Density		kg/m³	507.6
Saturated Vapour Density at nBPt		kg/m³	5.26
Vapour Pressure	25°C	bara	6.652
Latent Heat of Evaporation at nBPt			216.8
Coefficient of Thermal Expansion	LIQ. 0–20°C	°C	0.002766
Solubility of HFA 134a in Water	20°C / 1 atm	% w/w	0.0773
Solubility of Water in HFA 134a	25°C / 1 atm	% w/w	0.11
Flammability in Air	1 atm		None
Autoignition Temperature		°C	770
Liquid Dielectric Constant	25°C		9.51
Vapour Dielectric Constant	25°C / 1 atm		1.014
Dielectric Strength	R12 = 1		0.5
Dipole Moment			2.06

Leading medical propellant used in MDIs throughout the world

Our state-of-the-art manufacturing facilities in the North West of England have been designed and constructed to stringent current Good Manufacturing Practice (cGMP) standards.

Physical properties of Zephex® 134a

PROPERTY	CONDITION	UNITS	VALUE
Molecular Weight			102.03
Boiling Point	1 atm	°C	-26.1
Melting Point		°C	-103.0
Critical Temperature		°C	101.0
Critical Pressure		bara	40.56
Critical Volume		m³/kg	1.97 × 10⁻³
Critical Density		kg/m³	507.6
Saturated Vapour Density at nBPt		kg/m³	5.26
Vapour Pressure	25°C	bara	6.652
Latent Heat of Evaporation at nBPt			216.8
Coefficient of Thermal Expansion	LIQ. 0–20°C	°C	0.002766
Solubility of HFA 134a in Water	20°C / 1 atm	% w/w	0.0773
Solubility of Water in HFA 134a	25°C / 1 atm	% w/w	0.11
Flammability in Air	1 atm		None
Autoignition Temperature		°C	770
Liquid Dielectric Constant	25°C		9.51
Vapour Dielectric Constant	25°C / 1 atm		1.014
Dielectric Strength	R12 = 1		0.5
Dipole Moment			2.06

Zephex® 134a

Leading medical propellant used in MDIs throughout the world

Physical properties of Zephex® 134a

Continued supply of Zephex® 134a in line with market needs

Document downloads